SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY (SPECT)

A second radiotracer imaging modality, single photon emission computed tomography (SPECT), can achieve similar spatial resolution to PET. SPECT allows simultaneous detection of more than one radionuclide, although sensitivity is significantly lower than with PET. SPECT can be used for measuring perfusion, labeling cells, and for targeting cell-surface receptors and antigens via radiolabeled peptides and antibodies.

MODALITY

MODEL

MANUFACTURER

RESOLUTION

PET Focus 20 Siemens ~1.3mm
PET P4 Siemens ~1.8mm
PET microPETI Custom-built ~1.8mm
SPECT microSPECT Siemens ~1mm
CT microCAT II Siemens 25-150 um
CT microCT Custom-built ~ 300um
MRI Biospec 7T Bruker 50-250 um
Ultrasound Sequoia Siemens ~ 120 um
Optical IVIS 100 Xenogen ~ 2mm
Autoradiography Storm 860 Amersham Biosciences 50-100 um




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