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[18F]Fluoride
Uses: [18F]Fluoride in aqueous solution is used primarily to image bone and therefore can provide information on features of the skeleton.
Half life: 110 minutes
Availability: daily |
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[18F]FDG
Chemical name: [18F]Fluorodeoxyglucose
Uses: FDG, one of the most commonly utilized tracers for PET studies, is used to measure tissue glucose metabolism. It has important diagnostic and research applications in oncology, neurology, and cardiology.
Half life: 110 minutes
Availability: daily
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[18F]FHBG
Chemical name: 9-(4-[18F]Fluoro-3-Hydroxymethylbutyl) Guanine
Uses: Reporter probe for the herpes simplex virus type 1 thymidine kinase (HSV1-tk) gene, which is transfected into malignant cells in experimental suicide gene therapy.
Half life: 110 minutes
Availability: daily
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[18F]FLT
Chemical name: [18F]Fluorothymidine
Uses: A marker for cell proliferation that is more specific for tumor imaging than [18F]FDG.
Half life: 110 minutes
Availability: daily
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[18F]FMISO
Chemical name: [18F]Fluoromisonidazole
Uses: Used for the detection of hypoxia in tumors, myocardial infarcts, or cerebral ischemia.
Half life: 110 minutes
Availability: daily
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[64Cu]Cu-PTSM
Chemical name: [64Cu]Cu-pyruvaldehyde-bis[N4-methylthiosemicarbazone]
Uses: Tracer for blood flow, hypoxia, and cell binding studies.
Half life: 12.7 hours
Availability: 64Cu is available approximately every two weeks. Please inquire for specific dates.
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[64Cu]Cu-chelate-conjugates (Above)
Uses: Molecular probes (e.g., antibodies, peptides, and nanoparticles) can be conjugated to chelating (metal binding) agents, which bind 64Cu. The example structure is a protein conjugated to the 64Cu binding chelator tetraazacyclotetradecane (TETA).
Half life: 12.7 hours
Availability: 64Cu is available approximately every two weeks. Please inquire for specific dates.
Special notes: CMGI Radiochemistry can conjugate a chelating agent to a client-supplied molecular probe as a custom synthesis; or the client may provide a chelate-conjugated probe.
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